Associated Papers
The Influence of OPRM1 A118G Polymorphism on the Dosage of Morphine in Patients with Advanced Liver Cancer.
Cheng H et al.
Journal of the College of Physicians and Surgeons--pakistan : Jcpsp, 2021
Stabilization of μ-opioid receptor facilitates its cellular translocation and signaling.
Zhu C et al.
Proteins, 2019
The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses.
Skorpen F et al.
Acta Anaesthesiologica Scandinavica, 2016
Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).
Knapman A et al.
British Journal of Pharmacology, 2015
Mu opioid receptor gene: new point mutations in opioid addicts.
Dinarvand A et al.
Basic and Clinical Neuroscience, 2014
Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.
Gong XD et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2013
The genetics of the opioid system and specific drug addictions.
Levran O et al.
Human Genetics, 2012
Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.
Diatchenko L et al.
European Journal of Pain Supplements, 2011
The μ-opioid receptor variant N190K is unresponsive to peptide agonists yet can be rescued by small-molecule drugs.
Fortin JP et al.
Molecular Pharmacology, 2010
OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models.
Mague SD et al.
Drug and Alcohol Dependence, 2010
Novel linkage disequilibrium of single nucleotide polymorphisms in the transcriptional regulatory region of micro-opioid receptor gene in Japanese population.
Ono T et al.
Biological & Pharmaceutical Bulletin, 2009
Interindividual variability of methadone response: impact of genetic polymorphism.
Li Y et al.
Molecular Diagnosis & Therapy, 2008
The pharmacogenetics of analgesia.
Stamer UM et al.
Expert Opinion on Pharmacotherapy, 2007
Human kappa opioid receptor gene (OPRK1) polymorphism is associated with opiate addiction.
Gerra G et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2007
Modulation of Ca2+ channels by heterologously expressed wild-type and mutant human micro-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism.
Margas W et al.
Journal of Neurophysiology, 2007
[Are polymorphisms in the mu-opioid receptor important for opioid therapy?].
Lötsch J et al.
Schmerz (berlin, Germany), 2005
COMBINE genetics study: the pharmacogenetics of alcoholism treatment response: genes and mechanisms.
Goldman D et al.
Journal of Studies on Alcohol. Supplement, 2005
Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.
Smith RJ et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2005
Principles of pharmacogenetics--implications for the anaesthetist.
Iohom G et al.
British Journal of Anaesthesia, 2004
Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor.
Beyer A et al.
Journal of Neurochemistry, 2004
Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.
Lötsch J et al.
Clinical Pharmacokinetics, 2004
Neuropeptide gene polymorphisms and human behavioural disorders.
Inui A
Nature Reviews. Drug Discovery, 2003
Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?
Lötsch J et al.
Anesthesiology, 2002
A polymorphism (A118G) in the mu-opioid receptor gene affects the response to morphine-6-glucuronide in humans.
Höllt V
Pharmacogenetics, 2002
Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.
Wang D et al.
The Journal of Biological Chemistry, 2001
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
Befort K et al.
The Journal of Biological Chemistry, 2001
Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence.
Hoehe MR et al.
Human Molecular Genetics, 2000
Allelic variation S268P of the human mu-opioid receptor affects both desensitization and G protein coupling.
Koch T et al.
Molecular Pharmacology, 2000
Opioid Receptors Gene Polymorphism and Heroin Dependence in Iran.
Soleimani Asl S et al.
Basic and Clinical Neuroscience, 0