Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.D274N
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OPRM1

NM_000914.5:p.D274N

Associated Papers

Convergent Balancing Selection on the Mu-Opioid Receptor in Primates.

Sweeney CG et al.

Molecular Biology and Evolution, 2017

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

Knapman A et al.

British Journal of Pharmacology, 2015

Mu opioid receptor gene: new point mutations in opioid addicts.

Dinarvand A et al.

Basic and Clinical Neuroscience, 2014

The μ-opioid receptor variant N190K is unresponsive to peptide agonists yet can be rescued by small-molecule drugs.

Fortin JP et al.

Molecular Pharmacology, 2010

[Are polymorphisms in the mu-opioid receptor important for opioid therapy?].

Lötsch J et al.

Schmerz (berlin, Germany), 2005

Bioinformatic analysis of the human mu opioid receptor (OPRM1) splice and polymorphic variants.

Xin L et al.

Aaps Pharmsci, 2002

Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.

Wang D et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."