Varaico: Literature-Extracted Genetic Variants

Gene:ORAI2
Variant:p.R91W
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ORAI2

NM_001126340.3:p.R91W

Associated Papers

Store-Operated Calcium Entry Mediated by ORAI and STIM.

Nguyen NT et al.

Comprehensive Physiology, 2018

Orai3--the 'exceptional' Orai?

Shuttleworth TJ

The Journal of Physiology, 2012

Immunodeficiency due to defects in store-operated calcium entry.

Feske S

Annals of the New York Academy of Sciences, 2011

Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection.

McCarl CA et al.

Journal of Immunology (baltimore, Md. : 1950), 2010

CRAC channelopathies.

Feske S

Pflugers Archiv : European Journal of Physiology, 2010

Immunodeficiency due to mutations in ORAI1 and STIM1.

Feske S et al.

Clinical Immunology (orlando, Fla.), 2010

Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels.

Mignen O et al.

The Journal of Physiology, 2008

[Immunodeficiencies and pathologies associated with mutations in STIM/ORAI, a membrane complex in the heart of calcium signalling].

Le Deist F et al.

Medecine Sciences : M/s, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."