Associated Papers
Programmable protein stabilization with language model-derived peptide guides.
Hong L et al.
Nature Communications, 2025
OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination.
Peng L et al.
Cellular Oncology (dordrecht, Netherlands), 2024
Target deubiquitinase OTUB1 as a therapeatic strategy for BLCA via β-catenin/necroptosis signal pathway.
Liao Y et al.
International Journal of Biological Sciences, 2024
OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6.
Zhao Y et al.
Clinical and Translational Medicine, 2023
Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.
Li Y et al.
The Journal of Biological Chemistry, 2014
OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.
Herhaus L et al.
Nature Communications, 2013
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1.
Sun XX et al.
The Embo Journal, 2012
OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination.
Wu Q et al.
The Journal of Biological Chemistry, 0
Select a paper to view details