Varaico: Literature-Extracted Genetic Variants

Gene:OTUB1
Variant:p.T134R
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OTUB1

NM_017670.3:p.T134R

Associated Papers

The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1.

Bialas J et al.

The Journal of Biological Chemistry, 2019

OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination.

Pasupala N et al.

The Journal of Biological Chemistry, 2018

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.

Wiener R et al.

Nature Structural & Molecular Biology, 2013

OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.

Juang YC et al.

Molecular Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."