Varaico: Literature-Extracted Genetic Variants

Gene:OTULIN
Variant:p.W96R
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OTULIN

NM_138348.6:p.W96R

Associated Papers

Monogenic disorders of the TNF signalling pathway.

Lalaoui N et al.

Nature Reviews. Rheumatology, 2026

Met1-linked ubiquitination in cell signaling regulation.

Guo Y et al.

Biophysics Reports, 2024

OTULIN deficiency: focus on innate immune system impairment.

Dou B et al.

Frontiers in Immunology, 2024

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.

Hoste E et al.

Nature Communications, 2021

Fine-tuning ALK1 linear polyubiquitination to control angiogenesis.

Ten Dijke P et al.

Trends in Cell Biology, 2021

OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin.

Fu Y et al.

Molecular Cell, 2021

Ubiquitin-dependent and -independent functions of OTULIN in cell fate control and beyond.

Weinelt N et al.

Cell Death and Differentiation, 2021

Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation.

Douglas T et al.

The Journal of Biological Chemistry, 2020

Regulation of the endosomal SNX27-retromer by OTULIN.

Stangl A et al.

Nature Communications, 2019

The Met1-Linked Ubiquitin Machinery: Emerging Themes of (De)regulation.

Hrdinka M et al.

Molecular Cell, 2017

Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.

Sasaki K et al.

Immunological Reviews, 2015

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.

Rivkin E et al.

Nature, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."