Varaico: Literature-Extracted Genetic Variants

Gene:P2RX4
Variant:p.D280A
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P2RX4

NM_002560.3:p.D280A

Associated Papers

Intersubunit physical couplings fostered by the left flipper domain facilitate channel opening of P2X4 receptors.

Wang J et al.

The Journal of Biological Chemistry, 2017

Identification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains.

Tvrdonova V et al.

Plos One, 2014

Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.

Stojilkovic SS et al.

Cellular and Molecular Neurobiology, 2010

Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions.

Zemkova H et al.

Journal of Neurochemistry, 2007

An intersubunit zinc binding site in rat P2X2 receptors.

Nagaya N et al.

The Journal of Biological Chemistry, 2005

Molecular determinants of the agonist binding domain of a P2X receptor channel.

Yan Z et al.

Molecular Pharmacology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."