Varaico: Literature-Extracted Genetic Variants

Gene:P2RX7
Variant:p.R270C
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P2RX7

NM_002562.6:p.R270C

Associated Papers

Characterization of Common Genetic Variants in P2RX7 and Their Contribution to Chronic Pain Conditions.

Zorina-Lichtenwalter K et al.

The Journal of Pain, 2024

Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel.

Schäfer W et al.

Frontiers in Pharmacology, 2022

Association of a P2RX7 gene missense variant with brachycephalic dog breeds.

Sophocleous RA et al.

Animal Genetics, 2020

Single nucleotide polymorphisms associated with P2X7R function regulate the onset of gouty arthritis.

Tao JH et al.

Plos One, 2017

Haplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl.

Ide S et al.

Molecular Pain, 2014

R270C polymorphism leads to loss of function of the canine P2X7 receptor.

Spildrejorde M et al.

Physiological Genomics, 2014

Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients.

Wesselius A et al.

Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the Usa, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."