Varaico: Literature-Extracted Genetic Variants

Gene:P2RX7
Variant:p.D280A
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P2RX7

NM_002562.6:p.D280A

Associated Papers

Structural basis for the functional properties of the P2X7 receptor for extracellular ATP.

Jiang LH et al.

Purinergic Signalling, 2021

Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors.

Allsopp RC et al.

Molecular Pharmacology, 2018

Identification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains.

Tvrdonova V et al.

Plos One, 2014

Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions.

Zemkova H et al.

Journal of Neurochemistry, 2007

Molecular determinants of the agonist binding domain of a P2X receptor channel.

Yan Z et al.

Molecular Pharmacology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."