Varaico: Literature-Extracted Genetic Variants

Gene:P2RX7
Variant:p.V312A
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P2RX7

NM_002562.6:p.V312A

Associated Papers

Structural basis for the functional properties of the P2X7 receptor for extracellular ATP.

Jiang LH et al.

Purinergic Signalling, 2021

Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors.

Allsopp RC et al.

Molecular Pharmacology, 2018

Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120.

Allsopp RC et al.

Scientific Reports, 2017

Structural basis for subtype-specific inhibition of the P2X7 receptor.

Karasawa A et al.

Elife, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."