Associated Papers
Association of P2Y12 Polymorphisms With the Risk of Ischemic Stroke Subtypes.
Wu C et al.
Revista De Neurologia, 2026
Hepatic Cytochrome P450 Enzymatic System Interaction With Platelet Function and Cardiovascular Outcomes-Pharmacogenomic Impact on Inter-Organ Communication.
Figueiral M et al.
Comprehensive Physiology, 2025
A narrative review of research advancements in pharmacogenetics of cardiovascular disease and impact on clinical implications.
Shorbaji A et al.
Npj Genomic Medicine, 2025
Association of P2RY12 Gene Variants and Non-Genetic Factors With Clopidogrel Responsiveness in Vietnamese Patients After Percutaneous Coronary Intervention: A Cross-Sectional Study.
Ta Anh H et al.
Journal of Clinical Laboratory Analysis, 2025
Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.
Acosta-Monterrosa AA et al.
Frontiers in Pharmacology, 2025
Influence of Genetic and Epigenetic Factors of P2Y12 Receptor on the Safety and Efficacy of Antiplatelet Drugs.
Danielak D et al.
Cardiovascular Drugs and Therapy, 2024
Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation.
Su C et al.
Bmc Cardiovascular Disorders, 2023
Influence of genetic polymorphisms in P2Y12 receptor signaling pathway on antiplatelet response to clopidogrel in coronary heart disease.
Zhang YJ et al.
Bmc Cardiovascular Disorders, 2022
Clinical Relevance of a 16-Gene Pharmacogenetic Panel Test for Medication Management in a Cohort of 135 Patients.
Niedrig DF et al.
Journal of Clinical Medicine, 2021
Impact of genetic variants on major bleeding after percutaneous coronary intervention based on a prospective multicenter registry.
Cha JJ et al.
Scientific Reports, 2021
Association of clopidogrel high on-treatment reactivity with clinical outcomes and gene polymorphism in acute ischemic stroke patients: An observational study.
Fu H et al.
Medicine, 2020
A Genotype-Guided Strategy for Oral P2Y12 Inhibitors in Primary PCI.
Claassens DMF et al.
The New England Journal of Medicine, 2019
Blood platelet surface receptor genetic variation and risk of thrombotic episodes.
Szelenberger R et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 2019
Association between CYP2C19*2/*3 Polymorphisms and Coronary Heart Disease.
Zhang YY et al.
Current Medical Science, 2019
P2Y12 Polymorphisms and the Risk of Adverse Clinical Events in Patients Treated with Clopidogrel: A Meta-Analysis.
Zhao K et al.
Drug Research, 2019
Cytochrome P450 genotype-guided drug therapies: An update on current states.
Dong AN et al.
Clinical and Experimental Pharmacology & Physiology, 2018
CYP2C19 Genotype is an Independent Predictor of Adverse Cardiovascular Outcome in Iraqi Patients on Clopidogrel After Percutaneous Coronary Intervention.
Mohammad AM et al.
Journal of Cardiovascular Pharmacology, 2018
The influence of ABCB1 and P2Y12 genetic variants on clinical outcomes in Chinese intracranial artery stenosis patients.
Li X et al.
Clinical and Experimental Pharmacology & Physiology, 2018
The Prognostic Value of Combinations of Genetic Polymorphisms in the ITGB3, ITGA2, and CYP2C19*2 Genes in Predicting Cardiovascular Outcomes After Coronary Bypass Grafting.
Grinshtein YI et al.
Genetic Testing and Molecular Biomarkers, 2018
Study of the Association of PEAR1, P2Y12, and UGT2A1 Polymorphisms with Platelet Reactivity in Response to Dual Antiplatelet Therapy in Chinese Patients.
Zhang S et al.
Cardiology, 2018
Platelet membrane receptor P2Y12 H1/H2 polymorphism is highly associated with cerebral infarction: a case-control study.
Lu SJ et al.
Neuropsychiatric Disease and Treatment, 2018
Frequency of single nucleotide platelet receptor gene polymorphism (P2Y12-i744T>C) in coronary artery disease patients among Tamilian population.
Priyadharsini R et al.
Journal of Community Genetics, 2017
Does i-T744C P2Y12 Polymorphism Modulate Clopidogrel Response among Moroccan Acute Coronary Syndromes Patients?
Hassani Idrissi H et al.
Genetics Research International, 2017
Association of polymorphisms of platelet receptors GPIa (807C>T), GPVI (13254T>C), and P2Y12 (34C>T and H1/H2 haplotype) with increased risk of periprocedural bleeding in patients undergoing coronary angiography/percutaneous coronary intervention.
Sionova M et al.
Postepy W Kardiologii Interwencyjnej = Advances in Interventional Cardiology, 2017
Impact of genetic polymorphisms related to clopidogrel or acetylsalicylic acid pharmacology on clinical outcome in Chinese patients with symptomatic extracranial or intracranial stenosis.
Zhao Z et al.
European Journal of Clinical Pharmacology, 2016
Genotype Frequencies of CYP2C19, P2Y12 and GPIIIa Polymorphisms in Coronary Heart Disease Patients of Han Ethnicity, and Their Impact on Clopidogrel Responsiveness.
Ou W et al.
International Heart Journal, 2016
Relationship between clopidogrel-related polymorphisms and variable platelet reactivity at 1 year: A cohort study from Han Chinese.
Wang X et al.
Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences, 2016
Genotyping of CYP2C19 polymorphisms and its clinical validation in the ethnic Arab population.
Tayeb HT et al.
The Journal of Pharmacy and Pharmacology, 2015
Allele frequency distribution of CYP2C19*2 allelic variants associated with clopidogrel resistance in cardiac patients.
Rehman KU et al.
Experimental and Therapeutic Medicine, 2015
Use of genetic data to guide therapy in arterial disease.
Ross S et al.
Journal of Thrombosis and Haemostasis : Jth, 2015
Diversity of platelet function and genetic polymorphism in clopidogrel-treated Chinese patients.
Sun B et al.
Genetics and Molecular Research : Gmr, 2015
Clinical pharmacokinetics and pharmacodynamics of clopidogrel.
Jiang XL et al.
Clinical Pharmacokinetics, 2015
Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics.
Beitelshees AL et al.
Pharmacogenomics and Personalized Medicine, 2015
Effect of genetic variation in P2Y12 on TRAP-stimulated platelet response in healthy subjects.
Oestreich JH et al.
Journal of Thrombosis and Thrombolysis, 2014
Distribution of ABCB1, CYP3A5, CYP2C19, and P2RY12 gene polymorphisms in a Mexican Mestizos population.
Vargas-Alarcón G et al.
Molecular Biology Reports, 2014
Effect of P2Y1 and P2Y12 genetic polymorphisms on the ADP-induced platelet aggregation in a Korean population.
Kim KA et al.
Thrombosis Research, 2013
P2Y12 receptor gene polymorphism and antiplatelet effect of clopidogrel in patients with coronary artery disease after coronary stenting.
Zoheir N et al.
Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2013
Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response.
Gong IY et al.
European Heart Journal, 2012
Polymorphisms of platelet ADP receptor P2RY12 in the risk of venous thromboembolism in the Korean population.
Jang MJ et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2012
CYP2C19*2 and other genetic variants affecting platelet response to clopidogrel in patients undergoing percutaneous coronary intervention.
Kassimis G et al.
Thrombosis Research, 2012
High on-treatment platelet reactivity by ADP and increased risk of MACE in good clopidogrel metabolizers.
Marcucci R et al.
Platelets, 2012
The investigation of allele and genotype frequencies of CYP3A5 (1/3) and P2Y12 (T744C) in Iran.
Azarpira N et al.
Molecular Biology Reports, 2011
Pharmacogenomics of cardiovascular drugs and adverse effects in pediatrics.
Visscher H et al.
Journal of Cardiovascular Pharmacology, 2011
Individual variability in the disposition of and response to clopidogrel: pharmacogenomics and beyond.
Xie HG et al.
Pharmacology & Therapeutics, 2011
Identification of P2Y12 single-nucleotide polymorphisms and their influences on the variation in ADP-induced platelet aggregation.
Lee SJ et al.
Thrombosis Research, 2011
CYP2C19*2 and CYP2C9*3 alleles are associated with stent thrombosis: a case-control study.
Harmsze AM et al.
European Heart Journal, 2010
Prasugrel vs. clopidogrel for cytochrome P450 2C19-genotyped subgroups: integration of the TRITON-TIMI 38 trial data.
Sorich MJ et al.
Journal of Thrombosis and Haemostasis : Jth, 2010
Platelet pharmacogenomics.
Zuern CS et al.
Journal of Thrombosis and Haemostasis : Jth, 2010
Genetic causes of clopidogrel nonresponsiveness: which ones really count?
Momary KM et al.
Pharmacotherapy, 2010