Varaico: Literature-Extracted Genetic Variants

Gene:PAEP
Variant:p.T52T
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PAEP

NM_002571.4:p.T52T

Associated Papers

Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease.

Matthew AN et al.

Structure (london, England : 1993), 2018

Biophysical Studies on HCV 1a NS3/4A Protease and Its Catalytic Triad in Wild Type and Mutants by the In Silico Approach.

Palanisamy N et al.

Interdisciplinary Sciences, Computational Life Sciences, 2018

Protease Inhibitors Drug Resistance Mutations in Turkish Patients with Chronic Hepatitis C.

Sargin Altunok E et al.

International Journal of Infectious Diseases : Ijid : Official Publication of the International Society for Infectious Diseases, 2016

Evaluating the Role of Cellular Immune Responses in the Emergence of HCV NS3 Resistance Mutations During Protease Inhibitor Therapy.

Abdel-Hameed EA et al.

Viral Immunology, 2016

Mutational diversity of NS5A and NS3 during triple therapy (telaprevir, pegylated-interferon-α 2b and ribavirin) for genotype 1b chronic hepatitis C: The Kobe Hepatitis Therapeutic Group.

Bai F et al.

International Journal of Molecular Medicine, 2014

High-throughput screening (HTS) and hit validation to identify small molecule inhibitors with activity against NS3/4A proteases from multiple hepatitis C virus genotypes.

Lee H et al.

Plos One, 2013

Analysis of long-term persistence of resistance mutations within the hepatitis C virus NS3 protease after treatment with telaprevir or boceprevir.

Susser S et al.

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 2011

Phenotypic characterization of resistant Val36 variants of hepatitis C virus NS3-4A serine protease.

Zhou Y et al.

Antimicrobial Agents and Chemotherapy, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."