Varaico: Literature-Extracted Genetic Variants

Gene:PAK1
Variant:p.D389N
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PAK1

NM_002576.5:p.D389N

Associated Papers

Lessons from LIMK1 enzymology and their impact on inhibitor design.

Salah E et al.

The Biochemical Journal, 2019

Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.

Pellegrini E et al.

Plos One, 2017

Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases.

Xu Q et al.

Science Signaling, 2015

Structural insights into the autoactivation mechanism of p21-activated protein kinase.

Wang J et al.

Structure (london, England : 1993), 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."