Varaico: Literature-Extracted Genetic Variants

Gene:PAK6
Variant:p.K436M
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PAK6

NM_001395430.1:p.K436M

Associated Papers

PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.

Iannotta L et al.

Cell Death & Disease, 2024

Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation.

Su VL et al.

The Journal of Biological Chemistry, 2020

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Civiero L et al.

Frontiers in Molecular Neuroscience, 2017

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.

Civiero L et al.

Journal of Neurochemistry, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."