Associated Papers
Exploring breast cancer associated-gene panel for next-generation sequencing and identifying new, pathogenic variants in breast cancer from western China.
Cheng J et al.
Journal of Cancer, 2025
A rare PALB2 germline variant causing G2/M cell cycle arrest is associated with isolated myelosarcoma in infancy.
Beer A et al.
Molecular Genetics & Genomic Medicine, 2021
The p.Ser64Leu and p.Pro104Leu missense variants of PALB2 identified in familial pancreatic cancer patients compromise the DNA damage response.
Zhang Y et al.
Human Mutation, 2021
Functional characterization of 84 PALB2 variants of uncertain significance.
Wiltshire T et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2020
Molecular Mechanisms of PALB2 Function and Its Role in Breast Cancer Management.
Wu S et al.
Frontiers in Oncology, 2020
Functional Characterization of PALB2 Variants of Uncertain Significance: Toward Cancer Risk and Therapy Response Prediction.
Boonen RACM et al.
Frontiers in Molecular Biosciences, 2020
A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor.
Rodrigue A et al.
Nucleic Acids Research, 2019
Alternative transcript imbalance underlying breast cancer susceptibility in a family carrying PALB2 c.3201+5G>T.
Duran-Lozano L et al.
Breast Cancer Research and Treatment, 2019
Molecular analysis of PALB2-associated breast cancers.
Lee JEA et al.
The Journal of Pathology, 2018
PALB2 (partner and localizer of BRCA2).
Hanenberg H et al.
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.
Nepomuceno TC et al.
International Journal of Molecular Sciences, 2017
Perturbation of PALB2 function by the T413S mutation found in small cell lung cancer.
Bleuyard JY et al.
Wellcome Open Research, 2017
PALB2: research reaching to clinical outcomes for women with breast cancer.
Southey MC et al.
Hereditary Cancer in Clinical Practice, 2016
Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls.
Thompson ER et al.
Breast Cancer Research : Bcr, 2015
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
Park JY et al.
Oncogene, 2014
PALB2: the hub of a network of tumor suppressors involved in DNA damage responses.
Park JY et al.
Biochimica Et Biophysica Acta, 2014
Exploring the roles of PALB2 at the crossroads of DNA repair and cancer.
Pauty J et al.
The Biochemical Journal, 2014
Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer.
Hellebrand H et al.
Human Mutation, 2011