Varaico: Literature-Extracted Genetic Variants

Gene:PALB2
Variant:p.E42A
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PALB2

NM_024675.4:p.E42A

Associated Papers

Site-saturation functional screens identify PALB2 missense variants associated with increased breast cancer risk.

Boonen RACM et al.

Nature Communications, 2026

41554690 (PubMed )
Supplement: 41467_2025_67252_MOESM3_ESM.xlsx › Suppl._Data_1

PALB2 self-interaction controls homologous recombination.

Buisson R et al.

Nucleic Acids Research, 2012

PALB2 is an integral component of the BRCA complex required for homologous recombination repair.

Sy SM et al.

Proceedings of the National Academy of Sciences of the United States of America, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."