Varaico: Literature-Extracted Genetic Variants

Gene:PAM
Variant:p.S438P
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PAM

NM_001177306.2:p.S438P

Associated Papers

Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming.

Imai S et al.

Journal of Biochemistry, 2019

Suppressor Mutations for Presenilin 1 Familial Alzheimer Disease Mutants Modulate γ-Secretase Activities.

Futai E et al.

The Journal of Biological Chemistry, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."