Associated Papers
Mitochondrial iron deficiency triggers cytosolic iron overload in PKAN hiPS-derived astrocytes.
Santambrogio P et al.
Cell Death & Disease, 2024
Massive iron accumulation in PKAN-derived neurons and astrocytes: light on the human pathological phenotype.
Santambrogio P et al.
Cell Death & Disease, 2022
PKAN hiPS-Derived Astrocytes Show Impairment of Endosomal Trafficking: A Potential Mechanism Underlying Iron Accumulation.
Ripamonti M et al.
Frontiers in Cellular Neuroscience, 2022
iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases.
Hollingsworth EW et al.
Embo Molecular Medicine, 2017
29051230 (PubMed )
Supplement: EMMM-9-1742-s001.pdf
Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration.
Orellana DI et al.
Embo Molecular Medicine, 2016
Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients.
Santambrogio P et al.
Neurobiology of Disease, 2015
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.
Leoni V et al.
Molecular Genetics and Metabolism, 2012
Biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration.
Zhang YM et al.
The Journal of Biological Chemistry, 2006
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