Associated Papers
Genetic landscape of human oocyte/embryo defects.
Chen B et al.
Cell Genomics, 2026
Pannexin-1 channel activity regulates neurogenesis and cell survival in the developing cortex.
Hylton NK et al.
Biorxiv : the Preprint Server for Biology, 2026
Advances in monogenic female infertility.
Gu H et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025
The C-terminal activating domain promotes pannexin 1 channel opening.
Henze E et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
Advances in the genetic etiology of female infertility.
Gu R et al.
Journal of Assisted Reproduction and Genetics, 2024
A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death.
Zhou J et al.
Journal of Assisted Reproduction and Genetics, 2023
A novel heterozygous variant in PANX1 is associated with oocyte death and female infertility.
Wu XW et al.
Journal of Assisted Reproduction and Genetics, 2022
ConVarT: a search engine for matching human genetic variants with variants from non-human species.
Pir MS et al.
Nucleic Acids Research, 2022
Homozygous variants in PANX1 cause human oocyte death and female infertility.
Wang W et al.
European Journal of Human Genetics : Ejhg, 2021
Pannexin 1 Transgenic Mice: Human Diseases and Sleep-Wake Function Revision.
Battulin N et al.
International Journal of Molecular Sciences, 2021
Mutational effects of Pannexin 1 R217H depend on the carboxyl-terminus.
Purohit R et al.
Biochemical and Biophysical Research Communications, 2021
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein.
Nouri-Nejad D et al.
Molecular Biology of the Cell, 2021
Structural basis for gating mechanism of Pannexin 1 channel.
Mou L et al.
Cell Research, 2020
Cryo-EM structures of the ATP release channel pannexin 1.
Deng Z et al.
Nature Structural & Molecular Biology, 2020
Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region.
Sandilos JK et al.
The Journal of Biological Chemistry, 2012