Associated Papers
An update on the monogenic causes of Parkinson's disease: Impact on patient stratification and personalised medicine.
Asmi S et al.
Ageing Research Reviews, 2026
Exploring GBA1 gene in Parkinson's disease: Prevalence and variant spectrum from Asia minor.
Koç Yekedüz M et al.
Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025
Interaction Between α-Synuclein and DJ-1 in Parkinson's Disease.
Sobhifar P et al.
Brain Sciences, 2025
Interaction of α-synuclein with DJ-1 in homodimer and L166P mutant monomer forms in Parkinson's disease: a molecular dynamics study.
Alipour M et al.
Journal of Biomolecular Structure & Dynamics, 2025
Understanding Parkinson disease in Spain: Genetic and clinical insights.
Gómez-Garre P et al.
European Journal of Neurology, 2025
Deficiency of FABP7 Triggers Premature Neural Differentiation in Idiopathic Normocephalic Autism Organoids.
Han X et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2025
Genetic profiles of multiple system atrophy revealed by exome sequencing, long-read sequencing and spinocerebellar ataxia repeat expansion analysis.
Li XY et al.
European Journal of Neurology, 2024
Genetic and clinical study of PARK7 in Japanese Parkinson's disease.
Ishiguro M et al.
Heliyon, 2024
Motor and Non-motor Outcomes of Deep Brain Stimulation across the Genetic Panorama of Parkinson's Disease: A Multi-Scale Meta-Analysis.
Asimakidou E et al.
Movement Disorders Clinical Practice, 2024
Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.
Yang N et al.
Bmc Pediatrics, 2024
The reversible low-temperature instability of human DJ-1 oxidative states.
Andrews T et al.
Biopolymers, 2024
Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration.
Acar IE et al.
Investigative Ophthalmology & Visual Science, 2023
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Lv D et al.
Burns & Trauma, 2023
Impact of Single Amino Acid Substitutions in Parkinsonism-Associated Deglycase-PARK7 and Their Association with Parkinson's Disease.
Anjum F et al.
Journal of Personalized Medicine, 2022
Stepwise oxidations play key roles in the structural and functional regulations of DJ-1.
Song IK et al.
The Biochemical Journal, 2021
Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants.
Sánchez-Lanzas R et al.
Scientific Reports, 2021
An Emerging Role for Phosphoinositides in the Pathophysiology of Parkinson's Disease.
Schechter M et al.
Journal of Parkinson's Disease, 2021
PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson's Disease.
Li W et al.
Frontiers in Cell and Developmental Biology, 2021
Integrated sequencing and array comparative genomic hybridization in familial Parkinson disease.
Robak LA et al.
Neurology. Genetics, 2020
Association of rare variants in neurodegenerative genes with familial Alzheimer's disease.
Zhang W et al.
Annals of Clinical and Translational Neurology, 2020
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.
Cao Y et al.
Cell Research, 2020
Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth.
Chen R et al.
Cell Death & Disease, 2019
Genetic analyses of early-onset Alzheimer's disease using next generation sequencing.
Giau VV et al.
Scientific Reports, 2019
Mutations in Parkinson's Disease Associated Protein DJ-1 Alter the Energetics of DJ-1 Dimerization.
Kumar A et al.
Journal of Chemical Information and Modeling, 2019
Distinct Mechanisms of Pathogenic DJ-1 Mutations in Mitochondrial Quality Control.
Strobbe D et al.
Frontiers in Molecular Neuroscience, 2018
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Matsuda N et al.
Scientific Reports, 2017
Structural Biology of the DJ-1 Superfamily.
Smith N et al.
Advances in Experimental Medicine and Biology, 2017
Structural Characterization of Missense Mutations Using High Resolution Mass Spectrometry: A Case Study of the Parkinson's-Related Protein, DJ-1.
Ben-Nissan G et al.
Journal of the American Society for Mass Spectrometry, 2016
Parkinson's disease and age: The obvious but largely unexplored link.
Abdullah R et al.
Experimental Gerontology, 2015
Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2.
Björkblom B et al.
Molecular and Cellular Biology, 2014
Performance of protein disorder prediction programs on amino acid substitutions.
Ali H et al.
Human Mutation, 2014
DJ1 analysis in a large cohort of Italian early onset Parkinson Disease patients.
Sironi F et al.
Neuroscience Letters, 2013
Parkinson's disease-associated DJ-1 mutations increase abnormal phosphorylation of tau protein through Akt/GSK-3β pathways.
Wang Y et al.
Journal of Molecular Neuroscience : Mn, 2013
Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease.
Li B et al.
Journal of Molecular Neuroscience : Mn, 2013
Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
Björkblom B et al.
The Journal of Biological Chemistry, 2013
L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.
Ren H et al.
Molecular Neurodegeneration, 2012
Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1.
Madian AG et al.
Molecular & Cellular Proteomics : Mcp, 2012
Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.
Alvarez-Castelao B et al.
Biochimica Et Biophysica Acta, 2012
Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.
Ren H et al.
The Journal of Biological Chemistry, 2011
DJ-1 associates with synaptic membranes.
Usami Y et al.
Neurobiology of Disease, 2011
Olfaction in Parkin heterozygotes and compound heterozygotes: the CORE-PD study.
Alcalay RN et al.
Neurology, 2011
The genetics of Parkinson disease.
Bekris LM et al.
Journal of Geriatric Psychiatry and Neurology, 2010
Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study.
Alcalay RN et al.
Archives of Neurology, 2010
Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.
Logan T et al.
Biochemistry, 2010
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update.
Nuytemans K et al.
Human Mutation, 2010
DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders.
Kahle PJ et al.
Free Radical Biology & Medicine, 2009