Associated Papers
An update on the monogenic causes of Parkinson's disease: Impact on patient stratification and personalised medicine.
Asmi S et al.
Ageing Research Reviews, 2026
Large-scale genetic characterization of Parkinson's disease in the African and African admixed populations.
Akçimen F et al.
Brain : a Journal of Neurology, 2025
Interaction Between α-Synuclein and DJ-1 in Parkinson's Disease.
Sobhifar P et al.
Brain Sciences, 2025
Population-Specific Differences in Pathogenic Variants of Genes Associated with Monogenic Parkinson's Disease.
Flores-Ocampo V et al.
Genes, 2025
The reversible low-temperature instability of human DJ-1 oxidative states.
Andrews T et al.
Biopolymers, 2024
Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein.
Chiu CC et al.
Molecular Neurobiology, 2023
Cranial Dystonia as an Isolated Presentation of DJ-1 Disease: Case Report and Literature Review.
Rajapakshe I et al.
Movement Disorders Clinical Practice, 2023
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Lv D et al.
Burns & Trauma, 2023
Impact of Single Amino Acid Substitutions in Parkinsonism-Associated Deglycase-PARK7 and Their Association with Parkinson's Disease.
Anjum F et al.
Journal of Personalized Medicine, 2022
The QChip1 knowledgebase and microarray for precision medicine in Qatar.
Rodriguez-Flores JL et al.
Npj Genomic Medicine, 2022
Stepwise oxidations play key roles in the structural and functional regulations of DJ-1.
Song IK et al.
The Biochemical Journal, 2021
Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants.
Sánchez-Lanzas R et al.
Scientific Reports, 2021
An Emerging Role for Phosphoinositides in the Pathophysiology of Parkinson's Disease.
Schechter M et al.
Journal of Parkinson's Disease, 2021
High-depth African genomes inform human migration and health.
Choudhury A et al.
Nature, 2020
An in silico analysis of deleterious single nucleotide polymorphisms and molecular dynamics simulation of disease linked mutations in genes responsible for neurodegenerative disorder.
Pandey S et al.
Journal of Biomolecular Structure & Dynamics, 2020
Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth.
Chen R et al.
Cell Death & Disease, 2019
Impact of gene mutation in the development of Parkinson's disease.
Selvaraj S et al.
Genes & Diseases, 2019
Mutations in Parkinson's Disease Associated Protein DJ-1 Alter the Energetics of DJ-1 Dimerization.
Kumar A et al.
Journal of Chemical Information and Modeling, 2019
Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis.
MacPherson DJ et al.
The Journal of Biological Chemistry, 2019
Distinct Mechanisms of Pathogenic DJ-1 Mutations in Mitochondrial Quality Control.
Strobbe D et al.
Frontiers in Molecular Neuroscience, 2018
Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease.
Zeng XS et al.
Frontiers in Aging Neuroscience, 2018
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Matsuda N et al.
Scientific Reports, 2017
Structural Biology of the DJ-1 Superfamily.
Smith N et al.
Advances in Experimental Medicine and Biology, 2017
Early Onset Parkinson's disease due to DJ1 mutations: An Indian study.
Abbas MM et al.
Parkinsonism & Related Disorders, 2016
Structural Characterization of Missense Mutations Using High Resolution Mass Spectrometry: A Case Study of the Parkinson's-Related Protein, DJ-1.
Ben-Nissan G et al.
Journal of the American Society for Mass Spectrometry, 2016
Parkinson's disease and age: The obvious but largely unexplored link.
Abdullah R et al.
Experimental Gerontology, 2015
A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake.
Luk B et al.
Plos One, 2015
Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.
Holehouse AS et al.
Plos One, 2015
Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2.
Björkblom B et al.
Molecular and Cellular Biology, 2014
Atypical Parkinsonism-Dystonia Syndrome Caused by a Novel DJ1 Mutation.
Bras JM et al.
Movement Disorders Clinical Practice, 2014
DJ1 analysis in a large cohort of Italian early onset Parkinson Disease patients.
Sironi F et al.
Neuroscience Letters, 2013
Parkinson's disease-associated DJ-1 mutations increase abnormal phosphorylation of tau protein through Akt/GSK-3β pathways.
Wang Y et al.
Journal of Molecular Neuroscience : Mn, 2013
Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease.
Li B et al.
Journal of Molecular Neuroscience : Mn, 2013
Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
Björkblom B et al.
The Journal of Biological Chemistry, 2013
Rapid profiling of disease alleles using a tunable reporter of protein misfolding.
Pittman AM et al.
Genetics, 2012
L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.
Ren H et al.
Molecular Neurodegeneration, 2012
Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction.
Wang X et al.
Journal of Neurochemistry, 2012
Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1.
Madian AG et al.
Molecular & Cellular Proteomics : Mcp, 2012
Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.
Alvarez-Castelao B et al.
Biochimica Et Biophysica Acta, 2012
Genetics of Parkinson's disease.
Klein C et al.
Cold Spring Harbor Perspectives in Medicine, 2012
DJ-1 variants in Indian Parkinson's disease patients.
Sadhukhan T et al.
Disease Markers, 2012
Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.
Ren H et al.
The Journal of Biological Chemistry, 2011
DJ-1 associates with synaptic membranes.
Usami Y et al.
Neurobiology of Disease, 2011