Associated Papers
Computational association in parkinson's disease SNPs with brain structural and functional alterations.
Subramaniyan S et al.
Neurogenetics, 2025
A PARK7 Mutation-Induced Early-Onset Parkinson's Disease in a Moroccan Family: Expanding the Geographic Spectrum.
El Otmani H et al.
Movement Disorders Clinical Practice, 2025
A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis.
Arreola-Aldape CA et al.
Frontiers in Neuroscience, 2025
Genetic and clinical study of PARK7 in Japanese Parkinson's disease.
Ishiguro M et al.
Heliyon, 2024
The reversible low-temperature instability of human DJ-1 oxidative states.
Andrews T et al.
Biopolymers, 2024
Case report: Early-onset Parkinson's disease with lower limb spasticity in a new DJ-1/PARK7 patient.
Fujita M et al.
Frontiers in Neuroscience, 2024
Parkinson's disease - genetic cause.
Cherian A et al.
Current Opinion in Neurology, 2023
Genetic study of early-onset Parkinson's disease in the Malaysian population.
Tay YW et al.
Parkinsonism & Related Disorders, 2023
Molecular and Physiological Determinants of Amyotrophic Lateral Sclerosis: What the DJ-1 Protein Teaches Us.
Sandrelli F et al.
International Journal of Molecular Sciences, 2023
Cranial Dystonia as an Isolated Presentation of DJ-1 Disease: Case Report and Literature Review.
Rajapakshe I et al.
Movement Disorders Clinical Practice, 2023
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Lv D et al.
Burns & Trauma, 2023
Impact of Single Amino Acid Substitutions in Parkinsonism-Associated Deglycase-PARK7 and Their Association with Parkinson's Disease.
Anjum F et al.
Journal of Personalized Medicine, 2022
Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1.
Queliconi BB et al.
Journal of Cell Science, 2021
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder.
Jia X et al.
Molecular Psychiatry, 2021
The Parkinson's Disease-Associated Protein DJ-1 Protects Dictyostelium Cells from AMPK-Dependent Outcomes of Oxidative Stress.
Chen S et al.
Cells, 2021
Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants.
Sánchez-Lanzas R et al.
Scientific Reports, 2021
An Emerging Role for Phosphoinositides in the Pathophysiology of Parkinson's Disease.
Schechter M et al.
Journal of Parkinson's Disease, 2021
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.
Cao Y et al.
Cell Research, 2020
Misconnecting the dots: altered mitochondrial protein-protein interactions and their role in neurodegenerative disorders.
Zilocchi M et al.
Expert Review of Proteomics, 2020
DJ-1 in Parkinson's Disease: Clinical Insights and Therapeutic Perspectives.
Repici M et al.
Journal of Clinical Medicine, 2019
Genotype-Phenotype Relations for the Parkinson's Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review.
Kasten M et al.
Movement Disorders : Official Journal of the Movement Disorder Society, 2018
Distinct Mechanisms of Pathogenic DJ-1 Mutations in Mitochondrial Quality Control.
Strobbe D et al.
Frontiers in Molecular Neuroscience, 2018
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Matsuda N et al.
Scientific Reports, 2017
The Effects of Variants in the Parkin, PINK1, and DJ-1 Genes along with Evidence for their Pathogenicity.
Hauser DN et al.
Current Protein & Peptide Science, 2017
Structural Biology of the DJ-1 Superfamily.
Smith N et al.
Advances in Experimental Medicine and Biology, 2017
A novel homozygous DJ1 mutation causes parkinsonism and ALS in a Turkish family.
Hanagasi HA et al.
Parkinsonism & Related Disorders, 2016
Unexpected mitochondrial matrix localization of Parkinson's disease-related DJ-1 mutants but not wild-type DJ-1.
Kojima W et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2016
Parkinson's disease and age: The obvious but largely unexplored link.
Abdullah R et al.
Experimental Gerontology, 2015
Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2.
Björkblom B et al.
Molecular and Cellular Biology, 2014
Performance of protein disorder prediction programs on amino acid substitutions.
Ali H et al.
Human Mutation, 2014
DJ-1 facilitates the interaction between STAT1 and its phosphatase, SHP-1, in brain microglia and astrocytes: A novel anti-inflammatory function of DJ-1.
Kim JH et al.
Neurobiology of Disease, 2013
Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1.
Madian AG et al.
Molecular & Cellular Proteomics : Mcp, 2012
Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.
Alvarez-Castelao B et al.
Biochimica Et Biophysica Acta, 2012
Parkinson disease: insights in clinical, genetic and pathological features of monogenic disease subtypes.
Crosiers D et al.
Journal of Chemical Neuroanatomy, 2011
L10p and P158DEL DJ-1 mutations cause protein instability, aggregation, and dimerization impairments.
Ramsey CP et al.
Journal of Neuroscience Research, 2010
Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.
Logan T et al.
Biochemistry, 2010
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update.
Nuytemans K et al.
Human Mutation, 2010
PhenoHM: human-mouse comparative phenome-genome server.
Sardana D et al.
Nucleic Acids Research, 2010
DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders.
Kahle PJ et al.
Free Radical Biology & Medicine, 2009
Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene.
Keyser RJ et al.
Bmc Medical Genetics, 2009
The E163K DJ-1 mutant shows specific antioxidant deficiency.
Ramsey CP et al.
Brain Research, 2008
Structural impact of three Parkinsonism-associated missense mutations on human DJ-1.
Lakshminarasimhan M et al.
Biochemistry, 2008
Molecular pathways and genetic aspects of Parkinson's disease: from bench to bedside.
Di Napoli M et al.
Expert Review of Neurotherapeutics, 2007
Role of DJ-1 in Parkinson's disease.
Lev N et al.
Journal of Molecular Neuroscience : Mn, 2006
Novel mutation in the ALS2 gene in juvenile amyotrophic lateral sclerosis.
Kress JA et al.
Annals of Neurology, 2005