Associated Papers
Viral infection and brain inflammation with seizures in PARK7 deficiency.
Lønskov J et al.
Journal of Human Immunity, 2026
An update on the monogenic causes of Parkinson's disease: Impact on patient stratification and personalised medicine.
Asmi S et al.
Ageing Research Reviews, 2026
DJ-1 in Parkinson's disease: Its important role at endoplasmic reticulum-mitochondria contact sites.
Fan H et al.
Behavioural Brain Research, 2025
Interaction Between α-Synuclein and DJ-1 in Parkinson's Disease.
Sobhifar P et al.
Brain Sciences, 2025
The reaction mechanism for glycolysis side product degradation by Parkinson's disease-linked DJ-1.
Watanabe A et al.
The Journal of Cell Biology, 2025
Mitochondrial Dysfunction in Genetic and Non-Genetic Parkinson's Disease.
Lucchesi M et al.
International Journal of Molecular Sciences, 2025
Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy.
Padhan P et al.
Molecular and Cellular Neurosciences, 2025
Interaction of α-synuclein with DJ-1 in homodimer and L166P mutant monomer forms in Parkinson's disease: a molecular dynamics study.
Alipour M et al.
Journal of Biomolecular Structure & Dynamics, 2025
A mutation in the PRKAR1B gene drives pathological mechanisms of neurodegeneration across species.
Benjamin-Zukerman T et al.
Brain : a Journal of Neurology, 2024
Key genes and convergent pathogenic mechanisms in Parkinson disease.
Coukos R et al.
Nature Reviews. Neuroscience, 2024
Revisiting Glutamate Excitotoxicity in Amyotrophic Lateral Sclerosis and Age-Related Neurodegeneration.
Arnold FJ et al.
International Journal of Molecular Sciences, 2024
Assessing the reproducibility of machine-learning-based biomarker discovery in Parkinson's disease.
Ameli A et al.
Computers in Biology and Medicine, 2024
Effects of genetic variation on the structure of RNA and protein.
Kang J et al.
Proteomics, 2024
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.
Morrone Parfitt G et al.
Nature Communications, 2024
The reversible low-temperature instability of human DJ-1 oxidative states.
Andrews T et al.
Biopolymers, 2024
Case report: Early-onset Parkinson's disease with lower limb spasticity in a new DJ-1/PARK7 patient.
Fujita M et al.
Frontiers in Neuroscience, 2024
The Landscape of Monogenic Parkinson's Disease in Populations of Non-European Ancestry: A Narrative Review.
Koros C et al.
Genes, 2023
Loss of DJ-1 function contributes to Parkinson's disease pathogenesis in mice via RACK1-mediated PKC activation and MAO-B upregulation.
Liu LL et al.
Acta Pharmacologica Sinica, 2023
Parkinson's disease - genetic cause.
Cherian A et al.
Current Opinion in Neurology, 2023
Mechanisms of NURR1 Regulation: Consequences for Its Biological Activity and Involvement in Pathology.
García-Yagüe ÁJ et al.
International Journal of Molecular Sciences, 2023
Genetic study of early-onset Parkinson's disease in the Malaysian population.
Tay YW et al.
Parkinsonism & Related Disorders, 2023
Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein.
Chiu CC et al.
Molecular Neurobiology, 2023
Rare Catechol-O-methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets.
Larsen FB et al.
Biochemistry, 2023
PARK7/DJ-1 in microglia: implications in Parkinson's disease and relevance as a therapeutic target.
Lind-Holm Mogensen F et al.
Journal of Neuroinflammation, 2023
Cranial Dystonia as an Isolated Presentation of DJ-1 Disease: Case Report and Literature Review.
Rajapakshe I et al.
Movement Disorders Clinical Practice, 2023
DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis.
De Lazzari F et al.
Neurobiology of Disease, 2023
The Etiology of Parkinson's Disease: New Perspectives from Gene-Environment Interactions.
Bogers JS et al.
Journal of Parkinson's Disease, 2023
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Lv D et al.
Burns & Trauma, 2023
Post-translational modification and mitochondrial function in Parkinson's disease.
Luo S et al.
Frontiers in Molecular Neuroscience, 2023
Human Induced Pluripotent Stem Cell Phenotyping and Preclinical Modeling of Familial Parkinson's Disease.
Kim J et al.
Genes, 2022
Genetic landscape of early-onset dementia in Hungary.
Csaban D et al.
Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022
Impact of Single Amino Acid Substitutions in Parkinsonism-Associated Deglycase-PARK7 and Their Association with Parkinson's Disease.
Anjum F et al.
Journal of Personalized Medicine, 2022
Comparative analysis of web-based programs for single amino acid substitutions in proteins.
Choudhury A et al.
Plos One, 2022
Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1.
Queliconi BB et al.
Journal of Cell Science, 2021
Stepwise oxidations play key roles in the structural and functional regulations of DJ-1.
Song IK et al.
The Biochemical Journal, 2021
DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65.
Lin Z et al.
Cell Death & Disease, 2021
The C terminus of DJ-1 determines its homodimerization, MGO detoxification activity and suppression of ferroptosis.
Jiang L et al.
Acta Pharmacologica Sinica, 2021
KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability.
Wilson CJ et al.
International Journal of Molecular Sciences, 2021
Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants.
Sánchez-Lanzas R et al.
Scientific Reports, 2021
Modelling Parkinson's Disease: iPSCs towards Better Understanding of Human Pathology.
Avazzadeh S et al.
Brain Sciences, 2021
Dysfunction of Synaptic Vesicle Endocytosis in Parkinson's Disease.
Zou L et al.
Frontiers in Integrative Neuroscience, 2021
An Emerging Role for Phosphoinositides in the Pathophysiology of Parkinson's Disease.
Schechter M et al.
Journal of Parkinson's Disease, 2021