Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.D28A
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PARN

NM_002582.4:p.D28A

Associated Papers

Poly(A)-specific ribonuclease regulates the processing of small-subunit rRNAs in human cells.

Ishikawa H et al.

Nucleic Acids Research, 2017

PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells.

Zhang X et al.

Nucleic Acids Research, 2015

Destabilization of microRNAs in human cells by 3' deadenylation mediated by PARN and CUGBP1.

Katoh T et al.

Nucleic Acids Research, 2015

Dissimilar roles of the four conserved acidic residues in the thermal stability of poly(A)-specific ribonuclease.

He GJ et al.

International Journal of Molecular Sciences, 2011

Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.

Wu M et al.

Structure (london, England : 1993), 2009

Structural insight into poly(A) binding and catalytic mechanism of human PARN.

Wu M et al.

The Embo Journal, 2005

Identification of the active site of poly(A)-specific ribonuclease by site-directed mutagenesis and Fe(2+)-mediated cleavage.

Ren YG et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."