Varaico: Literature-Extracted Genetic Variants

Gene:PARP1
Variant:p.D993G
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PARP1

NM_001618.4:p.D993G

Associated Papers

The TIMELESS and PARP1 interaction suppresses replication-associated DNA gap accumulation.

Saldanha J et al.

Nucleic Acids Research, 2024

38801073 (PubMed )
Supplement: gkae445_supplemental_file.pdf

Transcription-replication conflicts underlie sensitivity to PARP inhibitors.

Petropoulos M et al.

Nature, 2024

Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection.

Rageul J et al.

Cell Reports, 2024

38393943 (PubMed )
Supplement: NIHMS1980911-supplement-1.pdf

Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.

Xie S et al.

Molecular Cell, 2015

Association of a missense single nucleotide polymorphism, Cys1367Arg of the WRN gene, with the risk of bone and soft tissue sarcomas in Japan.

Nakayama R et al.

Cancer Science, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."