Varaico: Literature-Extracted Genetic Variants

Gene:PARP1
Variant:p.K940R
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PARP1

NM_001618.4:p.K940R

Associated Papers

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc5.xlsx › Sheet1

Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.

Vanni I et al.

Journal of Translational Medicine, 2024

38750555 (PubMed )
Supplement: 12967_2024_5227_MOESM14_ESM.xlsx › S14

Genetic polymorphisms as potential pharmacogenetic biomarkers for platinum-based chemotherapy in non-small cell lung cancer.

Sito H et al.

Molecular Biology Reports, 2024

Virtual Screening of Different Subclasses of Lignans with Anticancer Potential and Based on Genetic Profile.

Maia MDS et al.

Molecules (basel, Switzerland), 2023

Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer.

Adamson AW et al.

Journal of Ovarian Research, 2023

37460928 (PubMed )
Supplement: 13048_2023_1234_MOESM2_ESM.xlsx › Table_S10__

Highlighting novel genes associated with the classical Rett syndrome patient from India.

Mohan G et al.

Genes & Diseases, 2022

Potential genetic biomarker of Saudi Arabian patients with colorectal cancer.

Younis NS et al.

European Review for Medical and Pharmacological Sciences, 2022

Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations.

Sprissler R et al.

Cancers, 2020

32570879 (PubMed )
Supplement: cancers-12-01618-s001.zip › cancers-817200-Supplementary_Materials3 › Supplementary_Table_S2.xlsx › Somatic_TSG_allVariants_

Identification of germline and somatic mutations in pancreatic adenosquamous carcinoma using whole exome sequencing.

Ma H et al.

Cancer Biomarkers : Section a of Disease Markers, 2020

31958074 (PubMed )
Supplement: sj-xlsx-1-cbm-10.3233_cbm-190236.xlsx › Germline

Characteristics of genomic alterations of lung adenocarcinoma in young never-smokers.

Luo W et al.

International Journal of Cancer, 2018

The investigation for potential modifier genes in patients with neurofibromatosis type 1 based on next-generation sequencing.

Yang F et al.

Oncotargets and Therapy, 2018

Tobacco habituated and non-habituated subjects exhibit different mutational spectrums in head and neck squamous cell carcinoma.

Rawal RM et al.

3 Biotech, 2015

28324520 (PubMed )
Supplement: 13205_2014_267_MOESM1_ESM.xlsx › WH

PARP-1 rs3219073 polymorphism may contribute to susceptibility to lung cancer.

Wang HT et al.

Genetic Testing and Molecular Biomarkers, 2014

Novel mutations of the PARP-1 gene associated with colorectal cancer in the Saudi population.

Alshammari AH et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer.

Buch SC et al.

Molecular Carcinogenesis, 2012

PARP1 polymorphisms increase the risk of gastric cancer in a Chinese population.

He W et al.

Molecular Diagnosis & Therapy, 2012

Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat.

Brevik A et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010

Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer.

Shiraishi K et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2010

Analysis of poly(ADP-ribose) polymerase-1 (PARP1) gene alteration in human germ cell tumor cell lines.

Ogino H et al.

Cancer Genetics and Cytogenetics, 2010

Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study.

Stern MC et al.

Journal of Nutrigenetics and Nutrigenomics, 2009

Analysis of genetic variants of the poly(ADP-ribose) polymerase-1 gene in breast cancer in French patients.

Cao WH et al.

Mutation Research, 2007

Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk.

Sakiyama T et al.

International Journal of Cancer, 2005

Poly(ADP-ribosyl)ation in relation to cancer and autoimmune disease.

Masutani M et al.

Cellular and Molecular Life Sciences : Cmls, 2005

Genetic alteration of poly(ADP-ribose) polymerase-1 in human germ cell tumors.

Shiokawa M et al.

Japanese Journal of Clinical Oncology, 2005

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