Associated Papers
Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery.
Rouleau-Turcotte É et al.
Molecular Cell, 2022
NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains.
Langelier MF et al.
Nature Communications, 2018
PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.
Dawicki-McKenna JM et al.
Molecular Cell, 2015
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