Associated Papers
Deciphering the Role of Sirtuin-1 Gene Polymorphism in Diabetic Nephropathy: A Systematic Review and Meta-Analysis.
Moin H et al.
Journal of Diabetes Research, 2026
Molecular Mechanisms of Preventable Causes of Oral Cancer and Precancer Through Polymorphism in DNA Base Excision Repair Genes in Patients with Tobacco Products Habits.
Sundaram E et al.
Journal of Maxillofacial and Oral Surgery, 2025
Targeting Poly (ADP-Ribose) Polymerase-1 for the Treatment of Neurodegenerative Diseases.
Polk S et al.
Chemical Biology & Drug Design, 2025
PARP-1 rs1136410 Polymorphism and Gastrointestinal Cancer Risk: A Meta-Analysis of Cancer-Type and Ethnic-Specific Associations.
Naseri A et al.
Medeniyet Medical Journal, 2025
Association of DNA damage response pathway genes with rheumatoid arthritis risks: a case-control study.
Hussain MZ et al.
Scientific Reports, 2025
Intramolecular Epistatic Interactions in Genetic Diseases.
Oliveira-Madureira T et al.
Journal of Inherited Metabolic Disease, 2025
PARP-1 gene promoter region may be associated with progression in multiple sclerosis.
Yilmaz B et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025
Comprehensive germline and somatic profiling of high-risk Thai breast cancer via next-generation sequencing.
Kamdee K et al.
Scientific Reports, 2025
Impact of a Cancer-Associated Mutation on Poly(ADP-ribose) Polymerase1 Inhibition.
Shanmugam N et al.
The Journal of Physical Chemistry. B, 2025
Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.
Kuras M et al.
Cancers, 2025
Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.
Canchi Sistla H et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025
Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology.
Kerle IA et al.
Npj Precision Oncology, 2025
Impact of a Cancer-Associated Mutation on Poly(ADP-ribose) Polymerase1 Inhibition.
Shanmugam N et al.
Biorxiv : the Preprint Server for Biology, 2024
An Analysis of Genetic Polymorphisms in 76 Genes Related to the Development of Ovarian Tumors of Different Aggressiveness.
Szafron LA et al.
International Journal of Molecular Sciences, 2024
Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences.
Burren OS et al.
Nature Genetics, 2024
Previously reported CCDC26 risk variant and novel germline variants in GALNT13, AR, and MYO10 associated with familial glioma in Finland.
Nurminen R et al.
Scientific Reports, 2024
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
Vanni I et al.
Journal of Translational Medicine, 2024
Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.
Yang N et al.
Bmc Pediatrics, 2024
ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines.
Lozinski M et al.
Oncotarget, 2024
Decreased DNA repair capacity caused by exposure to metal mixtures is modulated by the PARP1 rs1136410 variant in newborns from a polluted metropolitan area.
Paz-Sabillón M et al.
Environmental Research, 2024
Genetic polymorphisms as potential pharmacogenetic biomarkers for platinum-based chemotherapy in non-small cell lung cancer.
Sito H et al.
Molecular Biology Reports, 2024
Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.
Huang YC et al.
Journal of Personalized Medicine, 2023
Impact of DNA repair polymorphisms on DNA instability biomarkers induced by lead (Pb) in workers exposed to the metal.
Nunes EA et al.
Chemosphere, 2023
Updated protein domain annotation of the PARP protein family sheds new light on biological function.
Suskiewicz MJ et al.
Nucleic Acids Research, 2023
Bi-allelic mutation in SEC16B alters collagen trafficking and increases ER stress.
El-Gazzar A et al.
Embo Molecular Medicine, 2023
Olaparib-Resistant BRCA2MUT Ovarian Cancer Cells with Restored BRCA2 Abrogate Olaparib-Induced DNA Damage and G2/M Arrest Controlled by the ATR/CHK1 Pathway for Survival.
Biegała Ł et al.
Cells, 2023
Molecular Landscape of Pelvic Organ Prolapse Provides Insights into Disease Etiology.
Kluivers KB et al.
International Journal of Molecular Sciences, 2023
Genomic and biological aspects of resistance to selective poly(ADP-ribose) glycohydrolase inhibitor PDD00017273 in human colorectal cancer cells.
Tsuda K et al.
Cancer Reports (hoboken, N.j.), 2023
Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.
Álvarez-Prado ÁF et al.
Cell Reports. Medicine, 2023
Treatments against Polymorphosal discrepancies in Glioblastoma Multiforme.
Mukerjee N et al.
Metabolic Brain Disease, 2023
Common and rare variant associations with clonal haematopoiesis phenotypes.
Kessler MD et al.
Nature, 2022
Genetic susceptibility of bladder cancer in the Lebanese population.
Kourie HR et al.
Bmc Medical Genomics, 2022
Computational compensatory mutation discovery approach: Predicting a PARP1 variant rescue mutation.
Ravishankar K et al.
Biophysical Journal, 2022
A functional polymorphism in the poly(ADP-ribose) polymerase-1 gene increases the risk of endometrial carcinoma.
Zhao J et al.
Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 2022
Characterization of somatic mutations and pathway alterations during hepatocellular carcinoma vascular invasion using next-generation sequencing.
Li Q et al.
Journal of Gastrointestinal Oncology, 2022
PARP1 rs1136410 (A/G) polymorphism is associated with early age of onset of gallbladder cancer.
Anjali K et al.
European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ecp), 2022
Potential genetic biomarker of Saudi Arabian patients with colorectal cancer.
Younis NS et al.
European Review for Medical and Pharmacological Sciences, 2022
Prioritising positively selected variants in whole-genome sequencing data using FineMAV.
Wahyudi F et al.
Bmc Bioinformatics, 2021
SYNE1 Exonic Variant rs9479297 Contributes to Concurrent Hepatocellular and Transitional Cell Carcinoma Double Primary Cancer.
Chu YD et al.
Biomedicines, 2021
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
Li J et al.
Iscience, 2021
Genetic polymorphisms in DNA repair genes and hepatocellular carcinoma risk.
Ghaderi-Zefrehi H et al.
Dna Repair, 2021
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.
Wang Y et al.
Mutagenesis, 2021
PARP1 rs1136410 Val762Ala contributes to an increased risk of overall cancer in the East Asian population: a meta-analysis.
Xin Y et al.
The Journal of International Medical Research, 2021
Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Ogden TEH et al.
Nucleic Acids Research, 2021
Familial Colorectal Cancer and Genetic Susceptibility: Colorectal Risk Variants in First-Degree Relatives of Patients With Colorectal Cancer.
Gargallo-Puyuelo CJ et al.
Clinical and Translational Gastroenterology, 2021