Associated Papers
PARP1: Structural insights and pharmacological targets for inhibition.
Spiegel JO et al.
Dna Repair, 2021
Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage.
Steffen JD et al.
Nucleic Acids Research, 2016
PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.
Dawicki-McKenna JM et al.
Molecular Cell, 2015
Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.
Steffen JD et al.
Cancer Research, 2014
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