Varaico: Literature-Extracted Genetic Variants

Gene:PARP1
Variant:p.L33R
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PARP1

NM_001618.4:p.L33R

Associated Papers

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair.

Inanc B et al.

Nucleic Acids Research, 2025

40613707 (PubMed )
Supplement: gkaf574_supplemental_file.pdf

DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.

Taffoni C et al.

The Embo Journal, 2023

MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas.

Abe H et al.

Frontiers in Oncology, 2019

Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.

Jdey W et al.

Cancer Research, 2017

Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma.

Gill SJ et al.

Plos One, 2015

26505995 (PubMed )
Supplement: pone.0140988.s001.xlsx › Suppl.Data

PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.

Hu Y et al.

Cancer Discovery, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."