Varaico: Literature-Extracted Genetic Variants

Gene:PARP2
Variant:p.Y188F
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PARP2

NM_001042618.2:p.Y188F

Associated Papers

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites.

Lin X et al.

Nucleic Acids Research, 2022

PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage.

Riccio AA et al.

Nucleic Acids Research, 2016

PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.

Langelier MF et al.

Nucleic Acids Research, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."