Varaico: Literature-Extracted Genetic Variants

Gene:PAWR
Variant:p.A120T
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PAWR

NM_002583.4:p.A120T

Associated Papers

Platelet protease activated receptor 4 (PAR 4) receptor genotype is associated with an increased risk of preterm birth.

Boelig RC et al.

Journal of Thrombosis and Haemostasis : Jth, 2022

The PAR4 Platelet Thrombin Receptor Variant rs773902 does not Impact the Incidence of Thrombotic or Bleeding Events in a Healthy Older Population.

Selvadurai MV et al.

Thrombosis and Haemostasis, 2022

Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases.

Osman A et al.

Bmc Medical Genomics, 2022

Determination of PAR4 numbers on the surface of human platelets: no effect of the single nucleotide polymorphism rs773902.

Li S et al.

Platelets, 2021

The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y12 inhibition.

Whitley MJ et al.

Journal of Thrombosis and Haemostasis : Jth, 2018

Frequency of PAR4 Ala120Thr variant associated with platelet reactivity significantly varies across sub-Saharan African populations.

Heenkenda MK et al.

Blood, 2018

Protease-activated receptor-4 (PAR4) variant influences on platelet reactivity induced by PAR4-activating peptide through altered Ca2+ mobilization and ERK phosphorylation in healthy Japanese subjects.

Morikawa Y et al.

Thrombosis Research, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."