Associated Papers
Epigenetic, Genetic, and Functional Germline Alterations of PAX Genes in Human Pathology: A Comprehensive Update.
Gomez VL et al.
Current Issues in Molecular Biology, 2026
Familial Patterns in Acute Lymphoblastic Leukemia: Lessons From Three Siblings.
Khanahmad A et al.
Clinical Case Reports, 2025
IGH::IL3-Rearranged B-Cell Precursor Acute Lymphoblastic Leukemia With Hypereosinophilia in a Child With a Novel PAX5 Germline Variant.
Urbański B et al.
Genes, Chromosomes & Cancer, 2025
Overt and covert genetic causes of pediatric acute lymphoblastic leukemia.
Stoltze U et al.
Leukemia, 2025
Copy number alterations in pediatric B-cell precursor acute lymphoblastic leukemia patients and their association with patients' outcome.
Abdelfattah NE et al.
Annals of Hematology, 2025
Unraveling the Genetic Heterogeneity of Acute Lymphoblastic Leukemia Based on NGS Applications.
Ramírez Maldonado V et al.
Cancers, 2024
Diverse mechanisms of leukemogenesis associated with PAX5 germline mutation.
Bettini LR et al.
Leukemia, 2024
Proteome-scale characterisation of motif-based interactome rewiring by disease mutations.
Kliche J et al.
Molecular Systems Biology, 2024
GET: a foundation model of transcription across human cell types.
Fu X et al.
Biorxiv : the Preprint Server for Biology, 2024
Unraveling Copy Number Alterations in Pediatric B-Cell Acute Lymphoblastic Leukemia: Correlation with Induction Phase Remission Using MLPA.
Aisyi M et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2024
Case report: A familial B-acute lymphoblastic leukemia associated with a new germline pathogenic variant in PAX5. The first report in Mexico.
García-Solorio J et al.
Frontiers in Oncology, 2024
Essential role of the Pax5 C-terminal domain in controlling B cell commitment and development.
Gruenbacher S et al.
The Journal of Experimental Medicine, 2023
A novel germline PAX5 single exon deletion in a pediatric patient with precursor B-cell leukemia.
van Engelen N et al.
Leukemia, 2023
Transcription factor genetics and biology in predisposition to bone marrow failure and hematological malignancy.
Zerella JR et al.
Frontiers in Oncology, 2023
Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants.
Escudero A et al.
Leukemia, 2022
Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia.
Douglas SPM et al.
Scientific Reports, 2022
Delineation of a novel neurodevelopmental syndrome associated with PAX5 haploinsufficiency.
Gofin Y et al.
Human Mutation, 2022
PAX5 alterations in B-cell acute lymphoblastic leukemia.
Jia Z et al.
Frontiers in Oncology, 2022
Selection criteria for assembling a pediatric cancer predisposition syndrome gene panel.
Byrjalsen A et al.
Familial Cancer, 2021
Biologic and Therapeutic Implications of Genomic Alterations in Acute Lymphoblastic Leukemia.
Iacobucci I et al.
Journal of Clinical Medicine, 2021
Advances in germline predisposition to acute leukaemias and myeloid neoplasms.
Klco JM et al.
Nature Reviews. Cancer, 2021
Cell Fate Decisions: The Role of Transcription Factors in Early B-cell Development and Leukemia.
Fischer U et al.
Blood Cancer Discovery, 2020
Recent advances in genetic predisposition to pediatric acute lymphoblastic leukemia.
Bloom M et al.
Expert Review of Hematology, 2020
Genetic defects in hematopoietic transcription factors and predisposition to acute lymphoblastic leukemia.
Gocho Y et al.
Blood, 2019
Genetic Predisposition to Childhood Cancer in the Genomic Era.
Plon SE et al.
Annual Review of Genomics and Human Genetics, 2019
Germline Predisposition to Hematolymphoid Neoplasia.
Weinberg OK et al.
American Journal of Clinical Pathology, 2019
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
Bastian L et al.
Leukemia, 2019
Somatic and germline genomics in paediatric acute lymphoblastic leukaemia.
Pui CH et al.
Nature Reviews. Clinical Oncology, 2019
Transcription factor mutations as a cause of familial myeloid neoplasms.
Churpek JE et al.
The Journal of Clinical Investigation, 2019
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia.
Gu Z et al.
Nature Genetics, 2019
[Genetic predisposition to childhood cancer].
Ripperger T et al.
Der Pathologe, 2018
Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions.
Porter CC et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017
Germ line mutations associated with leukemias.
Porter CC
Hematology. American Society of Hematology. Education Program, 2016
Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.
Duployez N et al.
Expert Review of Hematology, 2016
GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.
Auer F et al.
European Journal of Medical Genetics, 2016
Genetic predisposition to acute lymphoblastic leukemia: Overview on behalf of the I-BFM ALL Host Genetic Variation Working Group.
Kratz CP et al.
European Journal of Medical Genetics, 2016
Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?
Srinivasan S et al.
Critical Reviews in Clinical Laboratory Sciences, 2016
Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.
Martín-Lorenzo A et al.
Cancer Discovery, 2015
PAX5 alterations in genetically unclassified childhood Precursor B-cell acute lymphoblastic leukaemia.
Stasevich I et al.
British Journal of Haematology, 2015
Cancer susceptibility syndromes in children in the area of broad clinical use of massive parallel sequencing.
Kuhlen M et al.
European Journal of Pediatrics, 2015
Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine.
Hunger SP et al.
Blood, 2015
Genomics in acute lymphoblastic leukaemia: insights and treatment implications.
Roberts KG et al.
Nature Reviews. Clinical Oncology, 2015
Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A.
Auer F et al.
Leukemia, 2014
Childhood B-acute lymphoblastic leukemia: a genetic update.
Woo JS et al.
Experimental Hematology & Oncology, 2014
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.
Shah S et al.
Nature Genetics, 2013