Varaico: Literature-Extracted Genetic Variants

Gene:PAX5
Variant:p.R140L
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PAX5

NM_016734.3:p.R140L

Associated Papers

An evaluation of genetic predisposition to congenital anomalies and pediatric cancer supports KAT6B as a novel neuroblastoma susceptibility gene.

Gu H et al.

Genetics in Medicine Open, 2025

Unraveling the Genetic Heterogeneity of Acute Lymphoblastic Leukemia Based on NGS Applications.

Ramírez Maldonado V et al.

Cancers, 2024

Case report: A familial B-acute lymphoblastic leukemia associated with a new germline pathogenic variant in PAX5. The first report in Mexico.

García-Solorio J et al.

Frontiers in Oncology, 2024

PAX2 Gene Mutation in Pediatric Renal Disorders-A Narrative Review.

Muntean C et al.

International Journal of Molecular Sciences, 2023

Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia.

Leongamornlert D et al.

Blood Advances, 2023

Transcription factor genetics and biology in predisposition to bone marrow failure and hematological malignancy.

Zerella JR et al.

Frontiers in Oncology, 2023

PAX5 alterations in B-cell acute lymphoblastic leukemia.

Jia Z et al.

Frontiers in Oncology, 2022

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia.

Li J et al.

Frontiers of Medicine, 2021

PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.

Bastian L et al.

Leukemia, 2019

PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia.

Gu Z et al.

Nature Genetics, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."