Associated Papers
PAXX/Ku interaction is rate limiting for repair of double-strand DNA breaks requiring end processing.
Gluza J et al.
The Journal of Biological Chemistry, 2025
Distinct functions of PAXX and MRI during chromosomal end joining.
Cisneros-Aguirre M et al.
Biorxiv : the Preprint Server for Biology, 2024
PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Seif-El-Dahan M et al.
Science Advances, 2023
Role of Paralogue of XRCC4 and XLF in DNA Damage Repair and Cancer Development.
Tang J et al.
Frontiers in Immunology, 2022
PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair.
Craxton A et al.
Nature Communications, 2018
Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.
Lescale C et al.
Cell Reports, 2016
DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Ochi T et al.
Science (new York, N.y.), 2015
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