Varaico: Literature-Extracted Genetic Variants

Gene:PBRM1
Variant:p.T232P
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PBRM1

NM_001405607.1:p.T232P

Associated Papers

Prediction tools for assessing functional impacts of gene mutations in Clear Cell Renal Cell Carcinoma: A comparative study.

Yang CH et al.

Computers in Biology and Medicine, 2025

Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma.

Schoenfeld DA et al.

Molecular Cancer Research : Mcr, 2022

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1.

Liao L et al.

Molecular Oncology, 2019

BAF180: Its Roles in DNA Repair and Consequences in Cancer.

Hopson S et al.

Acs Chemical Biology, 2017

Computational analysis of the mutations in BAP1, PBRM1 and SETD2 genes reveals the impaired molecular processes in renal cell carcinoma.

Piva F et al.

Oncotarget, 2015

26452128 (PubMed )
Supplement: oncotarget-06-32161-s002.xls › Predictions

BAF180 promotes cohesion and prevents genome instability and aneuploidy.

Brownlee PM et al.

Cell Reports, 2014

BAP1 loss defines a new class of renal cell carcinoma.

Peña-Llopis S et al.

Nature Genetics, 2012

22683710 (PubMed )
Supplement: NIHMS377160-supplement-Suppl__Data_3.xlsx › Suppl._Data_3

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

Varela I et al.

Nature, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."