Varaico: Literature-Extracted Genetic Variants

Gene:PC
Variant:p.K588*
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PC

NM_001040716.2:p.K588*

Associated Papers

Hepatitis B virus genotype distribution and mutation patterns: Insights and clinical implications for hepatitis B virus positive patients.

Ratnaparkhi MM et al.

World Journal of Experimental Medicine, 2025

Molecular analysis of HBV pre-core gene mutations in patients co-infected with HIV at a tertiary care hospital in North India.

Sami H et al.

Access Microbiology, 2025

Precore mutation enhances viral replication to facilitate persistent infection especially in HBeAg-negative patients.

Li G et al.

Virologica Sinica, 2024

Distribution and Clinical Significance of Hepatitis B virus A1762T/G1764A Double Mutation in Chronic Hepatitis B Patients: A Cross-Sectional Study.

Changsri K et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population.

Zhao Y et al.

Virology Journal, 2023

Core Promoter and Pre-Core Variants of the Hepatitis B Virus (HBV) Are Frequent in Chronic Hepatitis B HBeAg-Negative Patients Infected by Genotypes A and D.

Reuter T et al.

Viruses, 2023

Detection of Immune Escape and Basal Core Promoter/Precore Gene Mutations in Hepatitis B Virus Isolated from Asymptomatic Hospital Attendees in Two Southwestern States in Nigeria.

Sobajo OA et al.

Viruses, 2023

Precise analysis of the effect of basal core promoter/precore mutations on the main phenotype of chronic hepatitis B in mouse models.

Liu Y et al.

Journal of Medical Virology, 2020

The genetic polymorphism down-regulating HLA-DRB1 enhancer activity facilitates HBV persistence, evolution and hepatocarcinogenesis in the Chinese Han population.

Deng Y et al.

Journal of Viral Hepatitis, 2020

Next generation sequencing identifies baseline viral mutants associated with treatment response to pegylated interferon in HBeAg-positive chronic hepatitis B.

Chuaypen N et al.

Virus Genes, 2019

Pre-S/Surface and Core Promoter/Precore Mutations in Chronic Hepatitis B Patients with Severe Acute Exacerbation.

Chen YH et al.

Digestive Diseases and Sciences, 2019

HBV mutations in EnhII/BCP/PC region contribute to the prognosis of hepatocellular carcinoma.

Ge Z et al.

Cancer Medicine, 2019

The Effect of ICOS Polymorphism Interactions with HBV Mutations on HBV Subtype Infection Outcomes.

Song XM et al.

Annals of Hepatology, 2018

Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants.

Gao S et al.

Virology Journal, 2017

Viral minority variants in the core promoter and precore region identified by deep sequencing are associated with response to peginterferon and adefovir in HBeAg negative chronic hepatitis B patients.

Jansen L et al.

Antiviral Research, 2017

Different precore/core mutations of hepatitis B interact with, limit, or favor liver fibrosis severity.

Ducancelle A et al.

Journal of Gastroenterology and Hepatology, 2016

Association between hepatitis B virus basal core promoter/precore region mutations and the risk of hepatitis B-related acute-on-chronic liver failure in the Chinese population: an updated meta-analysis.

Nian X et al.

Hepatology International, 2016

Hepatitis B virus genotype, mutations, human leukocyte antigen polymorphisms and their interactions in hepatocellular carcinoma: a multi-centre case-control study.

Wen J et al.

Scientific Reports, 2015

Effect of functional nuclear factor-kappaB genetic polymorphisms on hepatitis B virus persistence and their interactions with viral mutations on the risk of hepatocellular carcinoma.

Zhang Q et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2014

[Relationship between hepatitis B virus polymerase gene mutation patterns of rtM204I/V and pre-core/basal core promoter mutations].

Yan L et al.

Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology, 2014

Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.

Datta S et al.

Plos One, 2014

Hepatitis B virus genetic variation and TP53 R249S mutation in patients with hepatocellular carcinoma in Thailand.

Thongbai C et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

Tracking the naturally occurring mutations across the full-length genome of hepatitis B virus of genotype D in different phases of chronic e-antigen-negative infection.

Ghosh S et al.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 2012

Prevalence of basal core promoter and precore mutations in Chinese chronic hepatitis B patients and correlation with serum HBeAG titers.

Qin Y et al.

Journal of Medical Virology, 2009

Molecular characterization of hepatitis B virus (HBV) isolates, including identification of a novel recombinant, in patients with acute HBV infection attending an Irish hospital.

Laoi BN et al.

Journal of Medical Virology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."