Associated Papers
Computational Study of PCSK9-EGFA Complex with Effective Polarizable Bond Force Field.
Chen J et al.
Frontiers in Molecular Biosciences, 2017
Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.
Zhang Y et al.
The Journal of Biological Chemistry, 2014
Loss- and gain-of-function PCSK9 variants: cleavage specificity, dominant negative effects, and low density lipoprotein receptor (LDLR) degradation.
Benjannet S et al.
The Journal of Biological Chemistry, 2012
New hypotheses about the structure-function of proprotein convertase subtilisin/kexin type 9: analysis of the epidermal growth factor-like repeat A docking site using WaterMap.
Pearlstein RA et al.
Proteins, 2010
Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants.
Bottomley MJ et al.
The Journal of Biological Chemistry, 2009
Investigations on the evolutionary conservation of PCSK9 reveal a functionally important protrusion.
Cameron J et al.
The Febs Journal, 2008
Functional analysis of sites within PCSK9 responsible for hypercholesterolemia.
Pandit S et al.
Journal of Lipid Research, 2008
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