Varaico: Literature-Extracted Genetic Variants

Gene:PDCD1
Variant:p.Y223F
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PDCD1

NM_005018.3:p.Y223F

Associated Papers

PD-1 interactome in osteosarcoma: identification of a novel PD-1/AXL interaction conserved between humans and dogs.

Dziubek K et al.

Cell Communication and Signaling : Ccs, 2024

Molecular mechanism of SHP2 activation by PD-1 stimulation.

Marasco M et al.

Science Advances, 2020

PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.

Wartewig T et al.

Nature, 2017

SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation.

Chemnitz JM et al.

Journal of Immunology (baltimore, Md. : 1950), 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."