Varaico: Literature-Extracted Genetic Variants

Gene:PDCD4
Variant:p.D253A
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PDCD4

NM_014456.5:p.D253A

Associated Papers

Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor.

Waters LC et al.

The Journal of Biological Chemistry, 2011

Structural basis for translational inhibition by the tumour suppressor Pdcd4.

Loh PG et al.

The Embo Journal, 2009

Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI.

Zakowicz H et al.

Rna (new York, N.y.), 2005

A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A.

Yang HS et al.

Molecular and Cellular Biology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."