Associated Papers
In vivo prime editing rescues photoreceptor degeneration in nonsense mutant retinitis pigmentosa.
Fu Y et al.
Nature Communications, 2025
A Penetrable AAV2 Capsid Variant for Efficient Intravitreal Gene Delivery to the Retina.
He X et al.
Investigative Ophthalmology & Visual Science, 2025
Establishment and visual analysis of CBA/J-Pde6bY347Y/Y347X and C3H/HeJ-Pde6bY347Y/Y347X mice.
Shindo M et al.
Experimental Animals, 2024
Does Background Matter? A Comparative Characterization of Mouse Models of Autosomal Retinitis Pigmentosa rd1 and Pde6b-KO.
Chirinskaite AV et al.
International Journal of Molecular Sciences, 2023
Identification and Characterization of Retinitis Pigmentosa in a Novel Mouse Model Caused by PDE6B-T592I.
Xia CH et al.
Biomedicines, 2023
Whole-exome sequencing prioritizes candidate genes for hereditary cataract in the Emory mouse mutant.
Bennett TM et al.
G3 (bethesda, Md.), 2023
Toward the Treatment of Inherited Diseases of the Retina Using CRISPR-Based Gene Editing.
Hernández-Juárez J et al.
Frontiers in Medicine, 2021
Targeting the photoreceptor cilium for the treatment of retinal diseases.
Ran J et al.
Acta Pharmacologica Sinica, 2020
A novel mutation in PDE6B in Spanish Water Dogs with early-onset progressive retinal atrophy.
Winkler PA et al.
Veterinary Ophthalmology, 2020
Gene editing prospects for treating inherited retinal diseases.
Benati D et al.
Journal of Medical Genetics, 2020
In vivo genome editing rescues photoreceptor degeneration via a Cas9/RecA-mediated homology-directed repair pathway.
Cai Y et al.
Science Advances, 2019
Pde6brd1 mutation modifies cataractogenesis in Foxe3rct mice.
Wada K et al.
Biochemical and Biophysical Research Communications, 2018
Retinal degeneration mutation in Sftpa1tm1Kor/J and Sftpd -/- targeted mice.
Bhatti F et al.
Plos One, 2018
CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.
Wu WH et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy, 2016
Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB).
Neuillé M et al.
Plos One, 2014
[Cause of retinitis pigmentosa and new therapeutics under development].
Sakamoto K et al.
Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica, 2011
Single-stranded oligonucleotide-mediated in vivo gene repair in the rd1 retina.
Andrieu-Soler C et al.
Molecular Vision, 2007
Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness.
Gal A et al.
Nature Genetics, 1994
Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa.
McLaughlin ME et al.
Nature Genetics, 1993