Varaico: Literature-Extracted Genetic Variants

Gene:PDGFRA
Variant:p.K646E
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PDGFRA

NM_006206.6:p.K646E

Associated Papers

miRNA Expression May Have Implications for Immunotherapy in PDGFRA Mutant GISTs.

Ravegnini G et al.

International Journal of Molecular Sciences, 2022

Correlation of treatment outcome in sanger/RT‑qPCR KIT/PDGFRA wild‑type metastatic gastrointestinal stromal tumors with next‑generation sequencing results: A single‑center report.

Unk M et al.

Oncology Reports, 2022

Oncogenic driver mutations predict outcome in a cohort of head and neck squamous cell carcinoma (HNSCC) patients within a clinical trial.

Fernández-Mateos J et al.

Scientific Reports, 2020

33024167 (PubMed )
Supplement: 41598_2020_72927_MOESM2_ESM.xlsx › Sheet1

Mutational spectrum and classification of novel mutations in patients with metastatic gastrointestinal stromal tumours.

Bombac A et al.

International Journal of Oncology, 2020

Gene Expression Profiling of PDGFRA Mutant GIST Reveals Immune Signatures as a Specific Fingerprint of D842V Exon 18 Mutation.

Indio V et al.

Frontiers in Immunology, 2020

Integrating miRNA and gene expression profiling analysis revealed regulatory networks in gastrointestinal stromal tumors.

Pantaleo MA et al.

Epigenomics, 2016

Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).

Nannini M et al.

Bmc Cancer, 2014

Dystrophin deregulation is associated with tumor progression in KIT/PDGFRA mutant gastrointestinal stromal tumors.

Pantaleo MA et al.

Clinical Sarcoma Research, 2014

Large-scale analysis of PDGFRA mutations in melanomas and evaluation of their sensitivity to tyrosine kinase inhibitors imatinib and crenolanib.

Dai J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

Differential expression of neural markers in KIT and PDGFRA wild-type gastrointestinal stromal tumours.

Pantaleo MA et al.

Histopathology, 2011

Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target.

Pantaleo MA et al.

International Journal of Cancer, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."