Varaico: Literature-Extracted Genetic Variants

Gene:PDGFRA
Variant:p.G652E
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PDGFRA

NM_006206.6:p.G652E

Associated Papers

A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer.

Rangarajan A et al.

Frontiers in Oncology, 2025

"De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.

Hadad S et al.

Acta Neuropathologica, 2023

38079020 (PubMed )
Supplement: 401_2023_2654_MOESM2_ESM.xlsx › Table_S3

Molecular Genetic Profile of 300 Japanese Patients with Diffuse Gliomas Using a Glioma-tailored Gene Panel.

Higa N et al.

Neurologia Medico-chirurgica, 2022

36031351 (PubMed )
Supplement: 1349-8029-62-0391-s006.pdf

IDH-Mutant Astrocytoma With Chromosome 19q13 Deletion Manifesting as an Oligodendroglioma-Like Morphology.

Miyake Y et al.

Journal of Neuropathology and Experimental Neurology, 2021

Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain.

Grunewald S et al.

Cancer Discovery, 2021

Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization.

Huss S et al.

Histopathology, 2012

Longitudinal profiling of IDH-mutant astrocytomas reveals acquired RAS-MAPK pathway mutations associated with inferior survival.

Rodriguez Almaraz E et al.

Neuro-oncology Advances, 0

40051658 (PubMed )
Supplement: vdaf024_suppl_supplementary_tables_s1-s4.xlsx › Table_S2
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."