Varaico: Literature-Extracted Genetic Variants

Gene:PDGFRA
Variant:p.G680R
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PDGFRA

NM_006206.6:p.G680R

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S6

Gene Mutations in Gastrointestinal Stromal Tumors: Advances in Treatment and Mechanism Research.

Cao L et al.

Global Medical Genetics, 2024

A Rare PDGFRA Exon 15 Germline Mutation Identified in a Patient With Phenotypic Manifestations Concerning for GIST-Plus Syndrome: A Case Report and Review of Literature.

Wang C et al.

International Journal of Surgical Pathology, 2023

An overview of agents and treatments for PDGFRA-mutated gastrointestinal stromal tumors.

Sun Y et al.

Frontiers in Oncology, 2022

Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain.

Grunewald S et al.

Cancer Discovery, 2021

Genomic and transcriptomic landscape of conjunctival melanoma.

Cisarova K et al.

Plos Genetics, 2020

33383577 (PubMed )
Supplement: pgen.1009201.s006.xlsx › Sheet1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."