Varaico: Literature-Extracted Genetic Variants

Gene:PDGFRA
Variant:p.L839P
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PDGFRA

NM_006206.6:p.L839P

Associated Papers

Relationship between gene mutations and protein expressions of PDGFR α and C-kit in gastrointestinal stromal tumors.

He JY et al.

International Journal of Clinical and Experimental Medicine, 2015

High-resolution melting analysis is a sensitive diagnostic tool to detect imatinib-resistant and imatinib-sensitive PDGFRA exon 18 mutations in gastrointestinal stromal tumors.

Künstlinger H et al.

Human Pathology, 2014

Large-scale analysis of PDGFRA mutations in melanomas and evaluation of their sensitivity to tyrosine kinase inhibitors imatinib and crenolanib.

Dai J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

A novel PDGFRA mutation in gastrointestinal stromal tumours, L839P, is sensitive to imatinib in vitro.

Bai C et al.

Oncology Letters, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."