Associated Papers
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
Paolino J et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023
Mining cancer genomes for change-of-metabolic-function mutations.
Tu KJ et al.
Communications Biology, 2023
An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors.
Hamada T et al.
Scientific Reports, 2022
Nationwide evaluation of mutation-tailored treatment of gastrointestinal stromal tumors in daily clinical practice.
Steeghs EMP et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021
Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies.
Toledo RA et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018
Integrative omics analyses broaden treatment targets in human cancer.
Sengupta S et al.
Genome Medicine, 2018
Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.
de Leng WW et al.
Plos One, 2016
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
Miller ML et al.
Cell Systems, 2015
High-resolution melting analysis is a sensitive diagnostic tool to detect imatinib-resistant and imatinib-sensitive PDGFRA exon 18 mutations in gastrointestinal stromal tumors.
Künstlinger H et al.
Human Pathology, 2014
Chromosomal aberrations in primary PDGFRA-mutated gastrointestinal stromal tumors.
Schaefer IM et al.
Human Pathology, 2014
Value of epithelioid morphology and PDGFRA immunostaining pattern for prediction of PDGFRA mutated genotype in gastrointestinal stromal tumors (GISTs).
Agaimy A et al.
International Journal of Clinical and Experimental Pathology, 2013
A sporadic multiple gastrointestinal stromal tumor with unique clinical and molecular features.
Pera M et al.
Human Pathology, 2011
The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro.
von Bubnoff N et al.
Oncogene, 2011
Site-dependent differential KIT and PDGFRA expression in gastric and intestinal gastrointestinal stromal tumors.
Haller F et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2007
Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors.
Haller F et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005