Varaico: Literature-Extracted Genetic Variants

Gene:PDHA1
Variant:p.S232A
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PDHA1

NM_000284.4:p.S232A

Associated Papers

Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation.

Li W et al.

Nature Communications, 2022

Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth.

Echeverri Ruiz NP et al.

Cancer & Metabolism, 2021

TGF-β1 is a regulator of the pyruvate dehydrogenase complex in fibroblasts.

Smith ER et al.

Scientific Reports, 2020

The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation.

Cerniglia GJ et al.

Molecular Cancer Therapeutics, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."