Varaico: Literature-Extracted Genetic Variants

Gene:PDK4
Variant:p.D394A
Back to variants list

PDK4

NM_002612.4:p.D394A

Associated Papers

Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.

Trinidad AG et al.

Oncogene, 2017

Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity.

Wynn RM et al.

The Journal of Biological Chemistry, 2008

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."