Associated Papers
PDX1 phosphorylation at S61 by mTORC1 links nutrient signaling to β cell function and metabolic disease.
Fan J et al.
Cell Reports, 2026
Unraveling the genetic basis of MODY: insights from next-generation sequencing.
Eser M et al.
Journal of Applied Genetics, 2025
Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: Lessons for precision medicine.
Kouidrat Y et al.
Diabetes & Metabolism, 2024
PDX-1: A Promising Therapeutic Target to Reverse Diabetes.
Zhang Y et al.
Biomolecules, 2022
Maturity-Onset Diabetes of the Young: Mutations, Physiological Consequences, and Treatment Options.
Younis H et al.
Journal of Personalized Medicine, 2022
First Japanese Family With PDX1-MODY (MODY4): A Novel PDX1 Frameshift Mutation, Clinical Characteristics, and Implications.
Yoshiji S et al.
Journal of the Endocrine Society, 2022
Iranian neonatal diabetes mellitus due to mutation in PDX1 gene: a case report.
Sahebi L et al.
Journal of Medical Case Reports, 2019
Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.
Yang Y et al.
Endocrine Reviews, 2016
Genomic sequencing of key genes in mouse pancreatic cancer cells.
Wang Y et al.
Current Molecular Medicine, 2012
The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1).
Stanojevic V et al.
Molecular and Cellular Endocrinology, 2005
Missense mutations in the human insulin promoter factor-1 gene are not a common cause of type 2 diabetes mellitus in Taiwan.
Shiau MY et al.
Journal of Endocrinological Investigation, 2004
Newly defined genetic diabetes syndromes: maturity onset diabetes of the young.
Winter WE
Reviews in Endocrine & Metabolic Disorders, 2003
Functional expression and analysis of the pancreatic transcription factor PDX-1 in yeast.
Ozcan S et al.
Biochemical and Biophysical Research Communications, 2002
Molecular etiologies of MODY and other early-onset forms of diabetes.
Shih DQ et al.
Current Diabetes Reports, 2002
Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood.
Hui H et al.
European Journal of Endocrinology, 2002
Mutations in the insulin promoter factor-1 gene in late-onset type 2 diabetes mellitus.
Reis AF et al.
European Journal of Endocrinology, 2000
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes.
Waeber G et al.
Nature Genetics, 2000
Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus.
Hani EH et al.
The Journal of Clinical Investigation, 1999
Pancreatic Duodenal Homeobox (PDX-1) in health and disease.
Melloul D et al.
Journal of Pediatric Endocrinology & Metabolism : Jpem, 0