Varaico: Literature-Extracted Genetic Variants

Gene:PDX1
Variant:p.G212R
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PDX1

NM_000209.4:p.G212R

Associated Papers

Prevalence and Clinical Characteristics of PDX1 Variant Induced Diabetes in Chinese Early-Onset Type 2 Diabetes.

Lian H et al.

The Journal of Clinical Endocrinology and Metabolism, 2023

Biophysical insights into glucose-dependent transcriptional regulation by PDX1.

Usher ET et al.

The Journal of Biological Chemistry, 2022

PDX-1: A Promising Therapeutic Target to Reverse Diabetes.

Zhang Y et al.

Biomolecules, 2022

First Japanese Family With PDX1-MODY (MODY4): A Novel PDX1 Frameshift Mutation, Clinical Characteristics, and Implications.

Yoshiji S et al.

Journal of the Endocrine Society, 2022

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.

Flannick J et al.

Nature, 2019

31118516 (PubMed )
Supplement: 41586_2019_1231_MOESM1_ESM.pdf

Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.

Yang Y et al.

Endocrine Reviews, 2016

Genome-wide scans reveal quantitative trait Loci on 8p and 13q related to insulin action and glucose metabolism: the San Antonio Family Heart Study.

Cai G et al.

Diabetes, 2004

PDX-1 and the pancreas.

Ashizawa S et al.

Pancreas, 2004

Functional expression and analysis of the pancreatic transcription factor PDX-1 in yeast.

Ozcan S et al.

Biochemical and Biophysical Research Communications, 2002

Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations.

Weng J et al.

Diabetologia, 2001

Pancreatic Duodenal Homeobox (PDX-1) in health and disease.

Melloul D et al.

Journal of Pediatric Endocrinology & Metabolism : Jpem, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."